产品货号：
Z39013
中文名称：
Tuberin/TSC2抗体
英文名称：
Anti-Tuberin/TSC2 Antibody (Clone#6I3)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Tuberin/TSC2 Antibody (Clone#6I3) |
| 指标别名 | LAM;TSC2;TSC4;Tuberin;tuberous sclerosis 2;Tuberous sclerosis 2 protein |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,FCM |
| 基因名称 | TSC2 |
| 克隆号 | 6I3 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | E.coli-derived human Tuberin recombinant protein (Position:H1611-V1807).Human Tuberin shares 94% and 90% amino acid (aa) sequence identity with mouse and rat Tuberin,respectively. |
| 实际分子量 | 280KD |
| 成分 | 200μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | protein G purified. |
| 浓度 | 200μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Tuberous sclerosis 2 protein,also known as TSC2 or Tuberin is a protein that is in humans.The chromosomal location of this gene is 16p13.3.Mutations in this gene lead to tuberous sclerosis complex.Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases.The protein associates with hamartin in a cytosolic complex,possibly acting as a chaperone for hamartin.This gene involved in microtubule-mediated protein transport,but this seems to be due to unregulated mTOR signaling.It stimulates weakly the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5 in vitro. |
| Uniprot ID | P49815 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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